Research Papers

The robust NMR toolbox for metabolomics

by Kousik Chandra, Samah Al-Harthi, Fatimah Almulhim, Abdul-Hamid Emwas, Łukasz Jaremko, Mariusz Jaremko
Molecular Omics Year: 2021 DOI: 10.1039/d1mo00118c

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Research article

Abstract

Here, we implemented and validated a suite of selective and non-selective CPMG-filtered 1D and 2D TOCSY/HSQC experiments for metabolomics research. They facilitated the unambiguous identification of metabolites embedded in broad lipid and protein signals. The 2D spectra improved non-targeted analysis by removing the background broad signals of macromolecules.